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Endothelial TRPV4 channels modulate vascular tone by Ca(2+)‐induced Ca(2+) release at inositol 1,4,5‐trisphosphate receptors
BACKGROUND AND PURPOSE: The TRPV4 ion channels are Ca(2+) permeable, non‐selective cation channels that mediate large, but highly localized, Ca(2+) signals in the endothelium. The mechanisms that permit highly localized Ca(2+) changes to evoke cell‐wide activity are incompletely understood. Here, we...
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| Published in: | Br J Pharmacol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692577/ https://ncbi.nlm.nih.gov/pubmed/31177523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14762 |
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