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Parameter estimation for sigmoid E(max) models in exposure-response relationship
The purpose of this simulation study is to explore the limitation of the population PK/PD analysis using data from a clinical study and to help to construct an appropriate PK/PD design that enable precise and unbiased estimation of both fixed and random PD parameters in PK/PD analysis under differen...
Gorde:
| Argitaratua izan da: | Transl Clin Pharmacol |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Korean Society for Clinical Pharmacology and Therapeutics
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7042008/ https://ncbi.nlm.nih.gov/pubmed/32133323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2017.25.2.74 |
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