CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments

CLASPs are conserved microtubule plus-end–tracking proteins that suppress microtubule catastrophes and independently localize to kinetochores during mitosis. Thus, CLASPs are ideally positioned to regulate kinetochore–microtubule dynamics required for chromosome segregation fidelity, but the underly...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Girão, Hugo, Okada, Naoyuki, Rodrigues, Tony A., Silva, Alexandra O., Figueiredo, Ana C., Garcia, Zaira, Moutinho-Santos, Tatiana, Hayashi, Ikuko, Azevedo, Jorge E., Macedo-Ribeiro, Sandra, Maiato, Helder
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041679/
https://ncbi.nlm.nih.gov/pubmed/31757788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201905080
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