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Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin

Natural Killer (NK) cells play an important role in antiviral defense and their potent effector function identifies them as key candidates for immunotherapeutic interventions in chronic viral infections. Their remarkable functional agility is achieved by virtue of a wide array of germline-encoded in...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Cubero, Elia Moreno, Ogbe, Ane, Pedroza-Pacheco, Isabela, Cohen, Myron S., Haynes, Barton F., Borrow, Persephone, Peppa, Dimitra
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041644/
https://ncbi.nlm.nih.gov/pubmed/32132995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00156
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