Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance

BACKGROUND: Differential expression of mucins has been associated with several cancers including colorectal cancer (CRC). In normal physiological conditions, secretory mucin MUC5AC is not expressed in the colonic mucosa, whereas its aberrant expression is observed during development of colon cancer...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Pothuraju, Ramesh, Rachagani, Satyanarayana, Krishn, Shiv Ram, Chaudhary, Sanjib, Nimmakayala, Rama Krishna, Siddiqui, Jawed A., Ganguly, Koelina, Lakshmanan, Imayavaramban, Cox, Jesse L., Mallya, Kavita, Kaur, Sukhwinder, Batra, Surinder K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041280/
https://ncbi.nlm.nih.gov/pubmed/32098629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01156-y
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