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Heterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression

BACKGROUND: Lung adenocarcinoma (LAC) is composed of lepidic, papillary, mucinous, micropapillary and solid components in its parenchyma. Complex responses to therapeutics result from intratumoral heterogeneity. However, it remains confused that what components in a mixed LAC tumor are responsible t...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Cai, Yiran, Wu, Hongbo, Shi, Xiaoqin, Dong, Yujie, Chang, Xiujun, Zhang, Li, Zhou, Lijuan, Su, Dan, Yang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041262/
https://ncbi.nlm.nih.gov/pubmed/32093629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6631-z
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