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An albumin-binding domain and targeting peptide-based recombinant protein and its enediyne-integrated analogue exhibit directional delivery and potent inhibitory activity on pancreatic cancer with K-ras mutation
Efficient enrichment and transmembrane transport of cytotoxic reagents are considered to be effective strategies to increase the efficiency and selectivity of antitumor drugs targeting solid tumors. In the present study, a recombinant protein ABD-LDP-Ec consisting of the albumin-binding domain (ABD)...
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| Udgivet i: | Oncol Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7041235/ https://ncbi.nlm.nih.gov/pubmed/32020213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7468 |
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