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MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering

BACKGROUND: In this paper, we explore the concept of multi-objective optimization in the field of metabolic engineering when both continuous and integer decision variables are involved in the model. In particular, we propose a multi-objective model that may be used to suggest reaction deletions that...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Andrade, Ricardo, Doostmohammadi, Mahdi, Santos, João L., Sagot, Marie-France, Mira, Nuno P., Vinga, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041195/
https://ncbi.nlm.nih.gov/pubmed/32093622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3377-1
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