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Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma

Targeted therapy for kidney cancer has achieved significant clinical results. However, because most patients who use targeted therapy will develop drug resistance, we still need to constantly explore new therapeutic targets. Although porcupine (PORCN) as a palmitoyltransferase plays a crucial role i...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Li, Jianyi, Wu, Guangzhen, Xu, Yingkun, Li, Jiatong, Ruan, Ningke, Chen, Yougen, Zhang, Qi, Xia, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040395/
https://ncbi.nlm.nih.gov/pubmed/32104684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2527643
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