Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma

Targeted therapy for kidney cancer has achieved significant clinical results. However, because most patients who use targeted therapy will develop drug resistance, we still need to constantly explore new therapeutic targets. Although porcupine (PORCN) as a palmitoyltransferase plays a crucial role i...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Li, Jianyi, Wu, Guangzhen, Xu, Yingkun, Li, Jiatong, Ruan, Ningke, Chen, Yougen, Zhang, Qi, Xia, Qinghua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040395/
https://ncbi.nlm.nih.gov/pubmed/32104684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2527643
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