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Nonspecific toxicities of Streptococcus pyogenes and Staphylococcus aureus dCas9 in Chlamydia trachomatis

Chlamydiae are common, important pathogens for humans and animals alike. Despite recent advancement in genetics, scientists are still searching for efficient tools to knock out or knock down the expression of chromosomal genes. We attempted to adopt a dCas9-based CRISPR interference (CRISPRi) techno...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: Wurihan, Wurihan, Huang, Yehong, Weber, Alec M, Wu, Xiang, Fan, Huizhou
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040368/
https://ncbi.nlm.nih.gov/pubmed/32011704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftaa005
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