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Nonspecific toxicities of Streptococcus pyogenes and Staphylococcus aureus dCas9 in Chlamydia trachomatis

Chlamydiae are common, important pathogens for humans and animals alike. Despite recent advancement in genetics, scientists are still searching for efficient tools to knock out or knock down the expression of chromosomal genes. We attempted to adopt a dCas9-based CRISPR interference (CRISPRi) techno...

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Bibliografski detalji
Izdano u:Pathog Dis
Glavni autori: Wurihan, Wurihan, Huang, Yehong, Weber, Alec M, Wu, Xiang, Fan, Huizhou
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040368/
https://ncbi.nlm.nih.gov/pubmed/32011704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftaa005
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