Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) patients exist an imbalance between regulatory T (Treg) and T helper 17 cells (Th17), which might be contributed by defective immune regulation of bone marrow derived mesenchymal stem cells (BM-MSCs) from SLE patients. Our microRNA array analysis showed markedly do...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Geng, Linyu, Tang, Xiaojun, Wang, Shiying, Sun, Yue, Wang, Dandan, Tsao, Betty P., Feng, Xuebing, Sun, Lingyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040072/
https://ncbi.nlm.nih.gov/pubmed/32133007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00233
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