A fluorescence-activatable reporter of flavivirus NS2B–NS3 protease activity enables live imaging of infection in single cells and viral plaques

The genus Flavivirus in the family Flaviviridae comprises many medically important viruses, such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus. The quest for therapeutic targets to combat flavivirus infections requires a better understanding of the kinetics of virus–host interact...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Arias-Arias, Jorge L., MacPherson, Derek J., Hill, Maureen E., Hardy, Jeanne A., Mora-Rodríguez, Rodrigo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Methods and Resources
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039541/
https://ncbi.nlm.nih.gov/pubmed/31919100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011319
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