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A fluorescence-activatable reporter of flavivirus NS2B–NS3 protease activity enables live imaging of infection in single cells and viral plaques

The genus Flavivirus in the family Flaviviridae comprises many medically important viruses, such as dengue virus (DENV), Zika virus (ZIKV), and yellow fever virus. The quest for therapeutic targets to combat flavivirus infections requires a better understanding of the kinetics of virus–host interact...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Arias-Arias, Jorge L., MacPherson, Derek J., Hill, Maureen E., Hardy, Jeanne A., Mora-Rodríguez, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039541/
https://ncbi.nlm.nih.gov/pubmed/31919100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011319
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