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Allosteric inhibition of the NS2B-NS3 protease from dengue virus

Dengue virus is the flavivirus that causes dengue fever, dengue hemorrhagic disease, and dengue shock syndrome, which are currently increasing in incidence worldwide. Dengue virus protease (NS2B-NS3pro) is essential for dengue virus infection and is thus a target of therapeutic interest. To date, at...

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Detalhes bibliográficos
Main Authors: Yildiz, Muslum, Ghosh, Sumana, Bell, Jeffrey A., Sherman, Woody, Hardy, Jeanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923078/
https://ncbi.nlm.nih.gov/pubmed/24164286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400612h
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