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Parallel evolution of chemokine binding by structurally related herpesvirus decoy receptors

A wide variety of pathogens target chemokine signaling networks in order to disrupt host immune surveillance and defense. Herein, we report a structural and mutational analysis of rodent herpesvirus Peru encoded R17, a potent chemokine inhibitor that sequesters CC- and C-chemokines with high affinit...

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Publicat a:Structure
Autors principals: Lubman, Olga Y., Fremont, Daved H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039123/
https://ncbi.nlm.nih.gov/pubmed/26671708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.10.018
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