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Parallel evolution of chemokine binding by structurally related herpesvirus decoy receptors
A wide variety of pathogens target chemokine signaling networks in order to disrupt host immune surveillance and defense. Herein, we report a structural and mutational analysis of rodent herpesvirus Peru encoded R17, a potent chemokine inhibitor that sequesters CC- and C-chemokines with high affinit...
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| Опубликовано в: : | Structure |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039123/ https://ncbi.nlm.nih.gov/pubmed/26671708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.10.018 |
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