Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition

Staufen1 (STAU1) is a dsRNA binding protein mediating mRNA transport and localization, translational control and STAU1-mediated mRNA decay (SMD). The STAU1 binding site (SBS) within human ADP-ribosylation factor1 (ARF1) 3′UTR binds STAU1 and this downregulates ARF1 cytoplasmic mRNA levels by SMD. Ho...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Yadav, Deepak Kumar, Zigáčková, Dagmar, Zlobina, Maria, Klumpler, Tomáš, Beaumont, Christelle, Kubíčková, Monika, Vaňáčová, Štěpánka, Lukavsky, Peter J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038937/
https://ncbi.nlm.nih.gov/pubmed/31875226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1163
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