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Engineering a CRISPR Interference System To Repress a Class 1 Integron in Escherichia coli

Microbial multidrug resistance (MDR) poses a huge threat to human health. Bacterial acquisition of MDR relies primarily on class 1 integron-involved horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). To date, no strategies other than the use of antibiotics can efficiently cope wit...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Li, Qingyang, Zhao, Peng, Li, Lili, Zhao, Haifeng, Shi, Lei, Tian, Pingfang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038292/
https://ncbi.nlm.nih.gov/pubmed/31871091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01789-19
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