Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

Ethionamide has proven efficacy against both drug-susceptible and some drug-resistant strains of Mycobacterium tuberculosis. Limited information on its pharmacokinetics in children is available, and current doses are extrapolated from weight-based adult doses. Pediatric doses based on more robust ev...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bjugård Nyberg, Henrik, Draper, Heather R., Garcia-Prats, Anthony J., Thee, Stephanie, Bekker, Adrie, Zar, Heather J., Hooker, Andrew C., Schaaf, H. Simon, McIlleron, Helen, Hesseling, Anneke C., Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038277/
https://ncbi.nlm.nih.gov/pubmed/31871093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01984-19
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