Pharmacokinetics and Safety of Ofloxacin in Children with Drug-Resistant Tuberculosis

Ofloxacin is widely used for the treatment of multidrug-resistant tuberculosis (MDR-TB). Data on its pharmacokinetics and safety in children are limited. It is not known whether the current internationally recommended pediatric dosage of 15 to 20 mg/kg of body weight achieves exposures reached in ad...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Garcia-Prats, Anthony J., Draper, Heather R., Thee, Stephanie, Dooley, Kelly E., McIlleron, Helen M., Seddon, James A., Wiesner, Lubbe, Castel, Sandra, Schaaf, H. Simon, Hesseling, Anneke C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Clinical Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576031/
https://ncbi.nlm.nih.gov/pubmed/26195507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01404-15
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