Model-Informed Drug Development, Pharmacokinetic/Pharmacodynamic Cutoff Value Determination, and Antibacterial Efficacy of Benapenem against Enterobacteriaceae

Benapenem is a novel carbapenem. The objective of this study was to determine the pharmacokinetic (PK)/pharmacodynamic (PD) cutoff values and evaluate the optimal administration regimens of benapenem for the treatment of bacterial infections via PK/PD modeling and simulation. Ertapenem was used as a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Ji, Xi-wei, Xue, Feng, Kang, Zi-sheng, Zhong, Wei, Kuan, Isabelle Hui-san, Yang, Xi-ping, Zhu, Xiao, Li, Yun, Lv, Yuan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038265/
https://ncbi.nlm.nih.gov/pubmed/31844001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01751-19
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker