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A Dimer, but Not Monomer, of Tobramycin Potentiates Ceftolozane against Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa and Delays Resistance Development

Ceftolozane-tazobactam is a potent β-lactam/β-lactamase inhibitor combination approved for the treatment of complicated intraabdominal and complicated urinary tract infections and, more recently, the treatment of hospital-acquired and ventilator-associated bacterial pneumonia. Although the activitie...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Idowu, Temilolu, Zhanel, George G., Schweizer, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038263/
https://ncbi.nlm.nih.gov/pubmed/31907191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02055-19
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