Short Proline-Rich Lipopeptide Potentiates Minocycline and Rifampin against Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa

A series of 16 short proline-rich lipopeptides (SPRLPs) were constructed to mimic longer naturally existing proline-rich antimicrobial peptides. Antibacterial assessment revealed that lipopeptides containing hexadecanoic acid (C(16)) possess optimal antibacterial activity relative to others with sho...

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發表在:Antimicrob Agents Chemother
Main Authors: Domalaon, Ronald, Sanchak, Yaroslav, Koskei, Linet Cherono, Lyu, Yinfeng, Zhanel, George G., Arthur, Gilbert, Schweizer, Frank
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914005/
https://ncbi.nlm.nih.gov/pubmed/29437631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02374-17
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