Polybasic peptide–levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria

To address the rising threat of multidrug-resistant (MDR) bacteria, new therapeutic strategies must be developed. Efficacious drug combinations consisting of existing antibiotics and enhancer biomolecules called adjuvants offers a viable strategy. We have previously reported antibiotic hybrids consi...

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Bibliografiske detaljer
Udgivet i:Medchemcomm
Main Authors: Berry, Liam, Domalaon, Ronald, Brizuela, Marc, Zhanel, George G., Schweizer, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2019
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482413/
https://ncbi.nlm.nih.gov/pubmed/31057731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00051h
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