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Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance

The resistance of tumors against anticancer drugs is a major impediment for chemotherapy. Tumors often develop multidrug resistance as a result of the cellular efflux of chemotherapeutic agents by ABC transporters such as P-glycoprotein (ABCB1/P-gp), Multidrug Resistance Protein 1 (ABCC1/MRP1), or B...

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發表在:Molecules
Main Authors: Tóth, Szilárd, Szepesi, Áron, Tran-Nguyen, Viet-Khoa, Sarkadi, Balázs, Német, Katalin, Falson, Pierre, Di Pietro, Attilio, Szakács, Gergely, Boumendjel, Ahcène
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038029/
https://ncbi.nlm.nih.gov/pubmed/32050702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030764
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