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Guanylyl Cyclase-cGMP Signaling Pathway in Melanocytes: Differential Effects of Altered Gravity in Non-Metastatic and Metastatic Cells

Human epidermal melanocytes as melanin producing skin cells represent a crucial barrier against UV-radiation and oxidative stress. It was shown that the intracellular signaling molecule cyclic guanosine-3′,5′-monophosphate (cGMP), generated by the guanylyl cyclases (GCs), e.g., the nitric oxide (NO)...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ivanova, Krassimira, Hemmersbach, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037284/
https://ncbi.nlm.nih.gov/pubmed/32046325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031139
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