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Interleukin-15 (dys)regulation of lymphoid homeostasis: Implications for therapy of autoimmunity and cancer
IL-15, a pleiotropic cytokine, stimulates generation of NK, NK-T, γδ, ILC1, and memory CD8 T cells. IL-15 disorders play pathogenetic roles in organ-specific autoimmune diseases including celiac disease. Diverse approaches are developed to block IL-15 action. IL-15 administered to patients with mali...
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| Published in: | J Exp Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037239/ https://ncbi.nlm.nih.gov/pubmed/31821442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191062 |
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