A Triple-Regulated Oncolytic Adenovirus Carrying MicroRNA-143 Exhibits Potent Antitumor Efficacy in Colorectal Cancer

The cancer-targeting gene virotherapy might be a useful strategy for the treatment of cancer, because it could combine the advantages of both gene therapy and virotherapy. This study aimed to construct a triple-regulated oncolytic adenovirus, Ad-RGD-Survivin-ZD55-miR-143, carrying the therapeutic ge...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Luo, Qifeng, Song, Hongming, Deng, Xiaochong, Li, Jiayi, Jian, Wei, Zhao, Junyong, Zheng, Xueyu, Basnet, Shiva, Ge, Haiyan, Daniel, Twingle, Xu, Bin, Fang, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036723/
https://ncbi.nlm.nih.gov/pubmed/32123722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.01.005
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