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A novel E1B55kDa-deleted oncolytic adenovirus carrying microRNA-143 exerts specific antitumor efficacy on colorectal cancer cells

The KRAS is an important and frequently mutated gene during colorectal carcinogenesis. The expression of miR-143 is often down-regulated and it might play an important role by targeting KRAS in colorectal cancer (CRC). The purpose of this study was to investigate the antitumor effects of miR-143 wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Luo, Qifeng, Basnet, Shiva, Dai, Zhenling, Li, Shuping, Zhang, Zhenyu, Ge, Haiyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040680/
https://ncbi.nlm.nih.gov/pubmed/27725862
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