Aromatic Residues at the Dimer–Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function

To prevent the accumulation of reactive oxygen species and limit associated damage to biological macromolecules, cells express a variety of oxidant-detoxifying enzymes, including peroxiredoxins. In Saccharomyces cerevisiae, the peroxiredoxin Tsa1 plays a key role in peroxide clearance and maintenanc...

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Библиографические подробности
Опубликовано в: :Chem Res Toxicol
Главные авторы: Loberg, Matthew A., Hurtig, Jennifer E., Graff, Aaron H., Allan, Kristin M., Buchan, John A., Spencer, Matthew K., Kelly, Joseph E., Clodfelter, Jill E., Morano, Kevin A., Lowther, W. Todd, West, James D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036284/
https://ncbi.nlm.nih.gov/pubmed/30701970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00346
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