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A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-human Primates

PURPOSE: Design of intravaginal rings (IVRs) for delivery of antiretrovirals is often guided by in vitro release under sink conditions, based on the assumption that in vivo release will follow a similar release profile. METHODS: We conducted a dose-ranging study in the female reproductive tract of p...

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Dettagli Bibliografici
Pubblicato in:Pharm Res
Autori principali: Su, Jonathan T., Teller, Ryan S., Srinivasan, Priya, Zhang, Jining, Martin, Amy, Sung, Samuel, Smith, James M., Kiser, Patrick F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036280/
https://ncbi.nlm.nih.gov/pubmed/28770490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2224-1
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