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The Long Road to the First FDA Approved Gene Therapy: Chimeric Antigen Receptor T Cells Targeting CD19
Thirty years after initial publications of the concept of a chimeric antigen receptor (CAR), the U.S. Food and Drug Administration (FDA) approved the first anti-CD19 CAR T cell therapy. Unlike other immunotherapies such as immune checkpoint inhibitors and bispecific antibodies, CAR T cells are uniqu...
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| Publicado en: | Cytotherapy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7036015/ https://ncbi.nlm.nih.gov/pubmed/32014447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2019.12.004 |
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