Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with Mycobacterium ulcerans. There is no effective vaccine. Here, we assessed an experimental prime-boost vaccine in a low-dose murine tail infection model. We used the enoyl reductase (ER) domain of the M. ulcer...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Mangas, Kirstie M., Buultjens, Andrew H., Porter, Jessica L., Baines, Sarah L., Marion, Estelle, Marsollier, Laurent, Tobias, Nicholas J., Pidot, Sacha J., Quinn, Kylie M., Price, David J., Kedzierska, Katherine, Zeng, Weiguang, Jackson, David C., Chua, Brendon Y., Stinear, Timothy P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035934/
https://ncbi.nlm.nih.gov/pubmed/31818964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00753-19
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