Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with Mycobacterium ulcerans. There is no effective vaccine. Here, we assessed an experimental prime-boost vaccine in a low-dose murine tail infection model. We used the enoyl reductase (ER) domain of the M. ulcer...

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Vydáno v:Infect Immun
Hlavní autoři: Mangas, Kirstie M., Buultjens, Andrew H., Porter, Jessica L., Baines, Sarah L., Marion, Estelle, Marsollier, Laurent, Tobias, Nicholas J., Pidot, Sacha J., Quinn, Kylie M., Price, David J., Kedzierska, Katherine, Zeng, Weiguang, Jackson, David C., Chua, Brendon Y., Stinear, Timothy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035934/
https://ncbi.nlm.nih.gov/pubmed/31818964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00753-19
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