Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with Mycobacterium ulcerans. There is no effective vaccine. Here, we assessed an experimental prime-boost vaccine in a low-dose murine tail infection model. We used the enoyl reductase (ER) domain of the M. ulcer...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Mangas, Kirstie M., Buultjens, Andrew H., Porter, Jessica L., Baines, Sarah L., Marion, Estelle, Marsollier, Laurent, Tobias, Nicholas J., Pidot, Sacha J., Quinn, Kylie M., Price, David J., Kedzierska, Katherine, Zeng, Weiguang, Jackson, David C., Chua, Brendon Y., Stinear, Timothy P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035934/
https://ncbi.nlm.nih.gov/pubmed/31818964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00753-19
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