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Difference in Strain Pathogenicity of Septicemic Yersinia pestis Infection in a TLR2(−/−) Mouse Model

Yersinia pestis is the causative agent of bubonic, pneumonic, and septicemic plague. We demonstrate that Toll-like receptor 2-deficient (TLR2(−/−)) mice are resistant to septicemic infection by the KIM5 strain of Y. pestis but not to infection by the CO92 Δpgm strain. This resistance is dependent on...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: O’Donnell, Kyle L., Knopick, Peter L., Larsen, Riley, Sarkar, Sanghita, Nilles, Matthew L., Bradley, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035930/
https://ncbi.nlm.nih.gov/pubmed/31907194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00792-19
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