PD-1 Expression on NK Cells in Malaria-Exposed Individuals Is Associated with Diminished Natural Cytotoxicity and Enhanced Antibody-Dependent Cellular Cytotoxicity

Natural killer (NK) cells are key effector cells of innate resistance capable of destroying tumors and virus-infected cells through cytotoxicity and rapid cytokine production. The control of NK cell responses is complex and only partially understood. PD-1 is an inhibitory receptor that regulates T c...

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Vydáno v:Infect Immun
Hlavní autoři: Moebius, Jacqueline, Guha, Rajan, Peterson, Mary, Abdi, Kaveh, Skinner, Jeff, Li, Shanping, Arora, Gunjan, Traore, Boubacar, Rajagopalan, Sumati, Long, Eric O., Crompton, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035929/
https://ncbi.nlm.nih.gov/pubmed/31907195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00711-19
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