Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

In malaria-naïve children and adults, Plasmodium falciparum-infected red blood cells (Pf-iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic areas where individuals experience repeated Pf infections over many years, the risk of Pf-iRBC-triggered inflammatory symptom...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Guha, Rajan, Mathioudaki, Anna, Doumbo, Safiatou, Doumtabe, Didier, Skinner, Jeff, Arora, Gunjan, Siddiqui, Shafiuddin, Li, Shanping, Kayentao, Kassoum, Ongoiba, Aissata, Zaugg, Judith, Traore, Boubacar, Crompton, Peter D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023468/
https://ncbi.nlm.nih.gov/pubmed/33822828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009430
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