Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3

Coxiella burnetii is an obligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containing vacuole (CCV). To establish this unique niche, C. burnetii requires the Dot/Icm type IV secretion system (T4SS) to translocate a cohort of effector proteins into the host...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Padmanabhan, Bhavna, Fielden, Laura F., Hachani, Abderrahman, Newton, Patrice, Thomas, David R., Cho, Hyun-Jung, Khoo, Chen Ai, Stojanovski, Diana, Roy, Craig R., Scott, Nichollas E., Newton, Hayley J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035922/
https://ncbi.nlm.nih.gov/pubmed/31818957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00534-19
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