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A deep adversarial variational autoencoder model for dimensionality reduction in single-cell RNA sequencing analysis

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) is an emerging technology that can assess the function of an individual cell and cell-to-cell variability at the single cell level in an unbiased manner. Dimensionality reduction is an essential first step in downstream analysis of the scRNA-seq dat...

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Publicado en:BMC Bioinformatics
Main Authors: Lin, Eugene, Mukherjee, Sudipto, Kannan, Sreeram
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035735/
https://ncbi.nlm.nih.gov/pubmed/32085701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3401-5
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