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Comparative analysis of ChIP-exo peak-callers: impact of data quality, read duplication and binding subtypes

BACKGROUND: ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables binding...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Sharma, Vasudha, Majumdar, Sharmistha
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035708/
https://ncbi.nlm.nih.gov/pubmed/32085702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3403-3
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