Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction

Increased expression of extracellular matrix (ECM) proteins in circulating tumor cells (CTCs) suggests potential function of cancer cell-produced ECM in initiation of cancer cell colonization. Here, we showed that collagen and heat shock protein 47 (Hsp47), a chaperone facilitating collagen secretio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xiong, Gaofeng, Chen, Jie, Zhang, Guoying, Wang, Shike, Kawasaki, Kunito, Zhu, Jieqing, Zhang, Yan, Nagata, Kazuhiro, Li, Zhenyu, Zhou, Binhua P., Xu, Ren
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035603/
https://ncbi.nlm.nih.gov/pubmed/32015106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911951117
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