Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats

BACKGROUND: Treatment of diabetic neuropathic pain (DNP) continues to be a major challenge, and underlying mechanisms of DNP remain elusive. We investigated treatment effects of B vitamins on DPN- and DNP-associated alterations of neurochemical signaling in the nociceptive dorsal root ganglion (DRG)...

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Bibliografische gegevens
Gepubliceerd in:Pain Res Manag
Hoofdauteurs: He, Duan-Duan, Gao, Yu, Wang, Shan, Xie, Zhong, Song, Xue-Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035549/
https://ncbi.nlm.nih.gov/pubmed/32104520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3740162
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