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Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats

Perioperative fentanyl has been reported to induce hyperalgesia and increase postoperative pain. In this study, we tried to investigate behavioral hyperalgesia, the expression of proinflammatory cytokines, such as interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α), and...

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Detalhes bibliográficos
Publicado no:Anesth Analg
Main Authors: Chang, Lu, Ye, Fang, Luo, Quehua, Tao, Yuanxiang, Shu, Haihua
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732642/
https://ncbi.nlm.nih.gov/pubmed/29135586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000002601
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