Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli

Bacterial biofilms, especially those associated with implanted medical devices, are difficult to eradicate. Curli amyloid fibers are important components of the biofilms formed by the Enterobacteriaceae family. Here, we show that a human monoclonal antibody with pan-amyloid-binding activity (mAb 3H3...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Tursi, Sarah A., Puligedda, Rama Devudu, Szabo, Paul, Nicastro, Lauren K., Miller, Amanda L., Qiu, Connie, Gallucci, Stefania, Relkin, Norman R., Buttaro, Bettina A., Dessain, Scott K., Tükel, Çagla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035420/
https://ncbi.nlm.nih.gov/pubmed/32081907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14685-3
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