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Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
The secondary active cation–chloride cotransporters (CCCs) utilize the existing Na(+) and/or K(+) gradients to move Cl(−) into or out of cells. NKCC1 is an intensively studied member of the CCC family and plays fundamental roles in regulating trans-epithelial ion movement, cell volume, chloride home...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035313/ https://ncbi.nlm.nih.gov/pubmed/32081947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14790-3 |
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