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Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy

The secondary active cation–chloride cotransporters (CCCs) utilize the existing Na(+) and/or K(+) gradients to move Cl(−) into or out of cells. NKCC1 is an intensively studied member of the CCC family and plays fundamental roles in regulating trans-epithelial ion movement, cell volume, chloride home...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yang, Xiaoyong, Wang, Qinzhe, Cao, Erhu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035313/
https://ncbi.nlm.nih.gov/pubmed/32081947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14790-3
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