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Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments

Colorectal cancer demonstrates intra-tumour heterogeneity formed by a hierarchical structure comprised of cancer stem cells (CSCs) and their differentiated progenies. The mechanism by which CSCs are maintained and differentiated needs to be further elucidated, and there is evidence that the tumour m...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Kawai, Shigeto, Yamazaki, Masaki, Shibuya, Keita, Yamazaki, Masaya, Fujii, Etsuko, Nakano, Kiyotaka, Suzuki, Masami
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035265/
https://ncbi.nlm.nih.gov/pubmed/32081957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60145-9
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