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BAX Depleted Retinal Ganglion Cells Survive and Become Quiescent following Optic Nerve Damage
BACKGROUND: Removal of the Bax gene from mice completely protects the somas of retinal ganglion cells (RGCs) from apoptosis following optic nerve injury. This makes BAX a promising therapeutic target to prevent neurodegeneration. In this study, Bax(+/−) mice were used to test the hypothesis that low...
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| Publicado no: | Mol Neurobiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035206/ https://ncbi.nlm.nih.gov/pubmed/31673950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01783-7 |
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