MYELOPEROXIDASE OXIDATION OF METHIONINE ASSOCIATES WITH EARLY CYSTIC FIBROSIS LUNG DISEASE

RATIONALE: Cystic fibrosis (CF) lung disease progressively worsens from infancy to adulthood. Disease-driven changes in early CF airway fluid metabolites may identify therapeutic targets to curb progression. METHODS: CF patients aged 12–38 months (n=24; 3/24 later denoted as CF screen positive, inco...

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Udgivet i:Eur Respir J
Main Authors: Chandler, Joshua D., Margaroli, Camilla, Horati, Hamed, Kilgore, Matthew B., Veltman, Mieke, Liu, H. Ken, Taurone, Alexander J., Peng, Limin, Guglani, Lokesh, Uppal, Karan, Go, Young-Mi, Tiddens, Harm A.W.M., Scholte, Bob J., Tirouvanziam, Rabindra, Jones, Dean P., Janssens, Hettie M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034951/
https://ncbi.nlm.nih.gov/pubmed/30190273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01118-2018
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